The Quebec Low Back Pain Study


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Pagé, Gabrielle M., Lacasse, Anaïs, Beaudet, Nicolas, Choinière, Manon, Deslauriers, Simon, Diatchenko, Luda, Dupuis, Laurent, Grégoire, Stéphanie, Hovey, Richard, Leclair, Erwan, Leonard, Guillaume, Meloto, Carolina B., Montagna, Francesca, Parent, Alexandre, Rainville, Pierre, Roy, Jean-Sébastien, Roy, Mathieu, Ware, Mark A., Wideman, Timothy H. et Stone, Laura S. (2020). The Quebec Low Back Pain Study. PAIN Reports , 5 (1). e799. doi:10.1097/PR9.0000000000000799 Repéré dans Depositum à

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Introduction: The neurobiological mechanisms underlying recovery from or persistence of low back pain (LBP) remain misunderstood, limiting progress toward effective management. We have developed an innovative two-tier design to study the transition from acute to chronic LBP. The objective of the first tier is to create a provincial web-based infrastructure to recruit and monitor the trajectory of individuals with acute LBP. The objective of the second tier is to fuel hypothesis-driven satellite data collection centers with specialized expertise to study the role of biomechanical, epigenetic, genetic, neuroanatomical, ontological, physiological, psychological, and socioeconomic factors in LBP chronicity.

Methods: This article describes the first tier of the protocol: establishment of the Core Dataset and Cohort. Adults with acute LBPwill be recruited through networks, media, and health care settings. A web-based interface will be used to collect self-reported variables at baseline and at 3, 6, 12, and 24months. Acute LBP will be defined according to the Dionne 2008 consensus. Measurements will include the Canadian minimum data set for chronic LBP research, DN4 for neuropathic pain, comorbidities, EQ-5D-5L for quality of life, and linkage with provincial medico-administrative databases. The primary outcome will be the transition to chronic LBP, as defined by Deyo 2014. Secondary outcomes include health care resource utilization, disability, sick leave, mood, and quality of life.

Perspective: This study brings together diverse research expertise to investigate the transition from acute to chronic LBP, characterize the progression to recovery or chronicity, and identify patterns associated with that progression.

Type de document: Article
Informations complémentaires: Licence d'utilisation : CC-BY 4.0
Mots-clés libres: Acute; Chronic; Persistence; Inception cohort; Low back pain; Two-stage sampling
Divisions: Santé
Date de dépôt: 18 mars 2020 18:07
Dernière modification: 26 mars 2020 15:20

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